Miani et al.:Understanding long-term effects of infant male circumcision

Zitat

Background
Following infant trauma, some individuals may develop dissociative
and aggressive behaviors and exhibit difficulties in recognizing
emotions.1,2 These traits are stereotypically associated with an
enhanced male endocrine configuration, represented by high
testosterone and low oxytocin levels, which have an impact on socio-
sexual cognition of the adult man.
Objectives
Due to the painful experience of the surgery, circumcision may be
considered as a perinatal traumatic experience, especially when
performed without analgesics. Along with a marked increase of
cortisol, changes in mother-infant interactions have been observed
after circumcision, including disrupted feeding and weaker
attachment.3 This might lead to a reduction in oxytocin (OXT) which in
turn affects testosterone (T) availability.4 Thus, we hypothesize that
circumcision might lead to an enhanced male endocrine configuration
characterized by high T and low OXT.

Methods
To explore this possibility, we are currently running an online survey on
early-circumcised (EC) and non-circumcised (NC) American men.
American individuals have been chosen because circumcision occurs
in the perinatal period (first week of life), it is not related to cultural or
religious practices, and about half of the male population is
circumcised, thus making subject recruitment easy without ethical
issues. Psychometric measures included in the survey were stress, 5
empathy,6 trust,7 personality traits,8 attachment style,9 sociosexuality,10
and sexual desire,11 traits previously linked to OXT and T levels.

Results
Our preliminary results (EC, N=75; NC, N=83) suggest that infant
circumcision seems to be associated with an increased attachment
avoidance (p<.01, d=.38) and decreased perspective-taking skills
(p<.05, d=.29) and trust (p<.05, d=.31). Although not significant in our
current small sample, EC scored higher in the sensation-seeking scale
(p=.16, d=.16). The two groups were not different in scales for
personality traits, perceived stress, and sexual libido (p>.05, d=.04),
yet, EC men score higher in sociosexuality (p=.001, d=.49), especially
in the desire facet (p<.001, d=.51). In the forest plot, the directionality
of effect size per each scale is displayed according to our hypotheses
(i.e., positive values = HA, negative values = H0), and the averaged
effect size is computed.

Discussion and Conclusions
EC men scored lower than NC in empathy, with a significant reduction in the dimension of perspective taking. We hypothesize that this might be
related to altered levels of circulating OXT and T. Previous works have shown that OXT selectively improves empathy accuracy,12 that OXT and
empathy toward a friend correlate,13 and that the OXT receptor gene polymorphism was associated with IRI scores.14 In addition, empathy towards
a stranger triggers release of OXT,15 while T is negatively associated with empathy scores.16 We found that EC scored significantly higher in
attachment avoidance, which has been previously associated with T levels.17 Individuals high on attachment-related avoidance do not trust others
and therefore tend to be self-reliant, independent, and non-affiliative. In fact, EC scored lower in trust and higher in sociosexuality. Trust is linked
positively with OXT and negatively with T.18 Sociosexuality, which is an orientation toward uncommitted sex, is predicted by T levels.19 Elevated T
levels might also be linked to sensation-seeking.20 These results point toward substantiating a trauma-related enhanced male endocrine
configuration in EC compared to NC men.

Alles anzeigen

https://www.researchgate.net/profile/Alessa…ircumcision.pdf

Ruhig, wart's ab!

Da werden jetzt subito von Forschern aus vorhautlosen Traditionsgemeinschaften wenigstens zehn diametral gegensätzliche Studien auf den Markt geworfen, damit der morriss-gewichtete Mittelwert in den Metastudien dann wieder passt...was wollen wir wetten? ...messerscharf, dass nicht sein kann, was nicht sein darf...

Sooo geht das doch nicht, es geht doch um eine gaaanz wichtige Tradition!

Wie hieß das noch so schön entlarvend, 2012? "Da haben wir doch unserere Studien!"

Zitat von Alessandro Miani

As far as I know, circumcision results in short-(and perhaps long-)term changes in the HPA system, for instance cortisol.

• Newborn males respond to circumcision with a marked reduction in oxygenation during the procedure, a cortisol surge, decreased wakefulness, increased vagal tone, and less interaction with their environment following the procedure
• There is a 50% increase over the baseline in heart rate in males undergoing the procedure and an increase in level of blood cortisol by a factor of three or more times has been recorded
• serum cortisol levels increased sharply immediately following infant circumcision and remained elevated for sev- eral days

Cortisol == Stresshormon

Interessant auch, dass EMLA sowieso, aber auch der PWB nicht viel bringt:

Zitat von Williamson PS, Evans ND.

Eleven male newborns were circumcised with a local dorsal penile nerve block, and 13 controls were circumcised without anesthetic. Matched pairs of pre- and postcircumcision cortisol levels in the two groups were compared. The adrenal cortisol response to surgery was not significantly reduced by the administration of lidocaine. Blood sampling and anesthetic injection of venipuncture alone did not evoke the adrenal response in uncircumcised control infants. Cortical input or secondary epinephrine elevation may be producing the cortisol elevation in infants despite regional blockage of the afferent nerve pathways.

Es gibt also überhaupt keine angemessene Betäubung für Verstümmelungen von Neugeborenen. Und das war schon vor über 30 Jahren bekannt.
Aber juckt das unsere Gesetzesgebieter? Unsere sogenannten "Volksvertreter"?

Zitat von Weguer

Die wievielte Studie ist das nun, die zu so einem Ergebnis kommt? Es müssen schon Dutzende sein.
Und es wird weiter verstümmelt. Augen zu, es wurde halt schon immer gemacht.

Ich fürchte, diese Studie ist Wasser auf die Mühlen von manchen Leuten, die meinen sie müssten ihre Söhne genitalverstümmeln:

Mehr Testosteron, mehr Aggressivität? Prima, die werden dann bessere Soldaten!
Gelobt sei, was hart macht!
Weniger Empathie? Gut so, die stört im harten Existenzkampf jeder gegen jeden doch nur!
Weniger Vertrauen - gut so - man kann "den anderen" gegenüber nicht misstrauisch genug sein!

Zitat von Sokrates

Wirklich? Glaubst Du das?

Ja, warum hätte ich das sonst geschrieben?

Das ist ein Urmotiv der BGM, die Abhärtung, dass da tapfere Soldaten draus werden. "Ganze Kerle" (die nicht mehr "ganz" sind), harte Jungs!

Zitat von Sokrates

Ich halte deine Schlussfolgerungen für reichlich übertrieben.

Das sind nicht meine Schlussfolgerungen.