- Official Post
Die umfangreichste open-access-Ausarbeitung über die Nerven im Penis die mir bisher untergekommen ist:
Alfonso Cepeda-Emiliani, María Otero-Alén, Juan Suárez-Quintanilla, Marina Gándara-Cortés, Tomás García-Caballero, Rosalía Gallego, Lucía García-Caballero
These findings reveal previously unrecognized transitions during fetal penile neural development and into adulthood, providing a foundation for the neurodevelopmental biology of the human penis and documenting the frenular delta's unique innervation. The characterization of penile neural components and the glans tunica albuginea addresses longstanding anatomical and sexological questions. Our results inform current debates on penile circumcision and neurotomy.
The frenular delta, which is part of the ventral prepuce, along with the rest of the prepuce and the glans, are the primary erogenous zones of the penis, containing dense neural structures essential for the perception of sexual pleasure
Recent immunohistochemical studies on preputial innervation6, 45, 46 have built on previous foundational work,11, 12 offering greater detail on the sensory corpuscles, FNEs, nerve bundles, and their molecular profiles within the prepuce. Beyond its rich sensory innervation, the prepuce contains a dense layer of smooth muscle forming its central axis (dartos)
The preputial dartoic innervation suggests that the dartos smooth muscle is neurally equipped to carry out complex physiological functions, enabling controlled contractions that contribute to penile skin tension,
The human penile prepuce contains a dense layer of innervated smooth muscle, known as the dartos layer, which forms the central axis of the prepuce between the dermis and lamina propria.11, 42 This muscular formation is embedded within a fibroelastic, highly vascular connective tissue, interspersed with aggregations of nerve bundles. The preputial dartos is sexually dimorphic, as the clitoral prepuce lacks a layer of smooth musculature,11, 90 suggesting that the dartos plays specialized functional roles in the penis. Histologically, the dartoic muscle bundles exhibit varied orientations, forming mosaic-like,91, 92 whorled,91 or plexiform6 patterns, which transition to a circular or transverse sphincteric configuration distally.11, 42
The dartos is richly innervated by FNEs and dense varicose neural plexuses intimately associated with the smooth myocytes and adjacent blood vessels, suggesting en passant synapses that enable neurotransmitter release along the nerve fibers.6, 47, 48